Welcome to the Zhao Lab
Many skeletal diseases are largely associated with or caused by inflammation. However, the underlying mechanisms are far from understood. We focus on osteoimmunology, an interdisciplinary field linking bone biology and the immune system. We are dedicated to advancing the scientific knowledge addressing how the immune system regulates the skeleton and identifying novel therapeutic targets for improving musculoskeletal diseases associated with inflammation.
Research
We study inflammatory regulation of signal transduction, gene regulation and epigenetics in cell differentiation, inflammation, in vivo disease models (such as inflammatory arthritis, osteoporosis, fracture healing, obese/diabetes), and more. Our work has been published into Nature Medicine, Journal of Experimental Medicine, Journal of Clinical Investigation, eLife, and Nature Communications.